Sirpiglenastat
Catalogue number:
CAY41293-5 mg
Supplier:
Size:
5 mg
Product is available in:
£829.00
Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2079939-05-0
Purity:
≥95%
Formulation:
A solid
Molecular Formula:
C22H27N5O5
Molecular Weight:
441.48048
Alternative Names:
n-acetyl-l-tryptophyl-6-diazo-5-oxo-l-norleucine, 1-methylethyl ester, drp-104
Product Description:
A prodrug form of 6-diazo-5-oxo-L-nor-leucine; decreases P493B lymphoma cell viability (EC50 = 10 µM); metabolized to DON in tumor tissues, but metabolized to an inactive metabolite in gastrointestinal tissues, in CES1-/- mice bearing EL4, MC-38, EO771, or 3LL tumors; reduces tumor size in EL4 tumor-bearing CES1-/- mice at 0.1, 0.3, and 1 mg/kg