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WAY-181187

Catalogue number:
CAY23461-50 mg
Supplier:
Size:
50 mg
Product is available in:
  • UK
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£616.00 Estimated delivery Wed 15 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

554403-49-5

Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C15H13ClN4O2S2

Molecular Weight:

380.87418

Alternative Names:

1-[(6-chloroimidazo[2,1-b]thiazol-5-yl)sulfonyl]-1h-indole-3-ethanamine, sax 187

Product Description:

A 5-HT6 receptor agonist; increases intracellular cAMP levels in HeLa cells expressing 5-HT6 (EC50 = 6.5 nM); selectively binds to 5-HT6 over 5-HT2B, 5-HT2C, and 5-HT7 (Kis = 2,458, 124, and 679 nM, respectively); selective for 5-HT6 over a panel of 31 receptors and ion channels at 100 nM; increases extracellular GABA levels in the rat frontal cortex at 10 mg/kg; reduces schedule-induced polydipsia, an adjunctive model of compulsive disorder, in rats at 178 mg/kg; has antidepressant-like activity in rats at 17 mg/kg and anxiolytic-like activity in rats at 10 and 17 mg/kg