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TAK-653

Catalogue number:
CAY42187-50 mg
Supplier:
Size:
50 mg
Product is available in:
  • UK
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£801.00 Estimated delivery Wed 6 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1358751-06-0

Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C19H23N3O3S

Molecular Weight:

373.47034

Alternative Names:

9-[4-(cyclohexyloxy)phenyl]-3,4- dihydro-7-methyl-pyrazino[2,1-c][1,2,4]thiadiazine, 2,2-dioxide, nbi 1065845

Product Description:

An AMPA receptor positive allosteric modulator; increases glutamate-induced calcium influx in CHO cells expressing human AMPA receptors (EC50 = 3.3 µM); potentiates AMPA receptor-mediated currents in rat primary hippocampal neurons (EC50= 4.4 µM); ameliorates MK-801-induced working memory deficits in the radial arm maze task in rats from 0.1-10 mg/kg; increases DMTS accuracy in cynomolgus monkeys at 0.06 mg/kg