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(E)-3-(2-Fluorophenyl)-N-(1H-indol-5-yl)acrylamide

Catalogue number:
CAY43022-10 mg
Supplier:
Size:
10 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£365.00 Estimated delivery Wed 31 Dec
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This product is for research use only and is not for human consumption or therapeutic use.
Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C17H13FN2O

Molecular Weight:

280.302403

Alternative Names:

mao-b inhibitor and nrf2 inducers compound 11

Product Description:

A MAO-B inhibitor and Nrf2 inducer; inhibits MAO-B (IC50 = 3.61 µM); increases levels of Nrf2 in a reporter assay using AREc32 cells (IC50 = 0.361 µM); scavenges peroxyl radicals in an ORAC assay (IC50 = 2.77 µM); inhibits LPS-induced increases in nitrite levels in BV-2 cells (EC50 = 11.6 µM); inhibits 6-OHDA- or rotenone- and oligomycin A-induced decreases in viability in SH-SY5Y cells at 1 µM