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PD 176252

Catalogue number:
CAY42037-1 mg
Supplier:
Size:
1 mg
Product is available in:
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£32.00 Estimated delivery Wed 24 Dec
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

204067-01-6

Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C32H36N6O5

Molecular Weight:

584.7

Alternative Names:

(αs)-n-[[1-(5-methoxy-2-pyridinyl)cyclohexyl]methyl]-α-methyl-α-[[[(4-nitrophenyl)amino]carbonyl]amino]-1h-indole-3-propanamide

Product Description:

A nonpeptide antagonist of BB1 and BB2 (Kis = 0.17 and 1 nM, respectively); induces calcium mobilization in HL-60 cells expressing FPR1 or FPR2/ALX (EC50s = 0.31 and 0.66 µM, respectively); inhibits the proliferation of C6 glioma cells (IC50 = 2 µM); increases social interaction in the social interaction test in rats at 100 ng/animal, i.c.v.; decreases the latency to feed in the novelty-suppressed feeding test at 10 mg/kg