Defensin NP-3A (60-93) (rabbit) (trifluoroacetate salt)

Name: Defensin NP-3A (60-93) (rabbit) (trifluoroacetate salt)
Brand: Cayman Chemical
SKU: CBSKU_202041600
Price: 62 GBP
Availability: InStock

Catalogue number:

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CAY41458-1 mg

Supplier:

Cayman Chemical

Size:

1 mg

Product is available in:

Currency:
GBP
EUR

£62.00

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Estimated delivery Wed 24 Dec
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This product is for research use only and is not for human consumption or therapeutic use.

Purity:

≥95%

Formulation:

A solid

Molecular Formula:

C163H265N63O44S6 • XCF3COOH

Molecular Weight:

4003.7

Alternative Names:

glycyl-l-isoleucyl-l-cysteinyl-l-alanyl-l-cysteinyl-l-arginyl-l-arginyl-l-arginyl-l-phenylalanyl-l-cysteinyl-l-prolyl-l-asparaginyl-l-seryl-l-a-glutamyl-l-arginyl-l-

Product Description:

An a-defensin peptide; active against C. albicans at 10 µg/ml; induces leakage of high molecular weight dextrans and low molecular weight reporters in combination with NP-1, NP-2, NP-3B, NP-4, and NP-5 in E. coli membrane mimics; inhibits phagocytosis in primary mouse macrophages in a concentration-dependent manner; induces histamine secretion in primary rat mast cells (EC50 = 70 nM); inhibits corticotropin-induced corticosterone production but does not decrease basal corticosterone levels in primary rat adrenal cells (IC50 = 33 pM)