Human MYT1L Antibody Pair

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Myelin transcription factor 1-like protein (MYT1L) is a crucial transcription factor that plays a significant role in neuronal development and differentiation. It is characterized by the presence of C2HC-type zinc fingers and a MYT1 domain, which are thought to function as transcriptional repressors. MYT1L is primarily expressed in the developing brain and is essential for enhancing neuronal identity by actively repressing several developmental pathways, including WNT and NOTCH. Dysregulation of MYT1L has been associated with various neurodevelopmental disorders, particularly autism spectrum disorder (ASD) and intellectual disability. Mutations or deletions in the MYT1L gene can lead to neurodevelopmental delays, behavioral phenotypes, and altered gene expression patterns that resemble those observed in ASD patients. Capture antibody: 100 µg. Detection antibody: 100 µg