NCT-58
Catalogue number:
T9996-100 mg
Supplier:
Size:
100 mg
Product is available in:
CAS Number:
2411429-33-7
Purity:
≥98%
Molecular Formula:
C27H34N2O5
Molecular Weight:
466.57
Alternative Names:
NCT58
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
NCT-58 is a potent C-terminal HSP90 inhibitor. NCT-58 does not induce the heat shock response (HSR). NCT-58 elicits anti-tumor activity via the simultaneous downregulation of HER family members as well as inhibition of Akt phosphorylation. NCT-58 kills Trastuzumab-resistant breast cancer stem-like cells. NCT-58 induces apoptosis in HER2-positive breast cancer cells.