(±)-Equol
Catalogue number:
T4000-50 mg
Supplier:
Size:
50 mg
Product is available in:
CAS Number:
94105-90-5
Purity:
≥98%
Molecular Formula:
C15H14O3
Molecular Weight:
242.27
Alternative Names:
Equol , (R,S)-Equol
- Data sheet: View or download
- MSDS: View or download
Product Description:
(±)-Equol ((R,S)-Equol) is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzen by human intestinal microflora. The estrogen receptor (ER) agonist activity of the naturally occurring (S)-enantiomer (EC50 = 85 and 65 nM for human ERα and ERβ, respectively) is similar to that of genistein but exceeds that of daidzein. (±)-Equol preferentially binds ERβ (Ki = 0.73 nM) and demonstrates approximately 9-fold lower affinity for ERα (Ki = 6.41 nM). (±)-Equol is also a potent antagonist of dihydrotestosterone, which has important implications for prostate cancer and other androgen-mediated pathologies.