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Dehydro Nifedipine

Catalogue number:
T36665-25 mg
Size:
25 mg
Product is available in:
  • UK
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CAS Number:

67035-22-7

Purity:

≥98%

Molecular Formula:

C17H16N2O6

Molecular Weight:

344.32

Alternative Names:

BAY-b 4759

Product Description:

Dehydro Nifedipine (BAY-b 4759) is the main metabolite of nifedipine in human plasma. Dehydro Nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 µM. Nifedipine is a calcium channel blocker used in the treatment of hypertension and angina. Dehydronifedipine is formed when it is metabolized by cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5.