Apratastat
Catalogue number:
T14312-10 mg
Supplier:
Size:
10 mg
Product is available in:
CAS Number:
287405-51-0
Molecular Formula:
C17H22N2O6S2
Molecular Weight:
414.5
- Data sheet: View or download
- MSDS: View or download
Product Description:
Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs) and it also can potently inhibit the release of TNF-α in vitro, ex vivo, and in vivo with IC50s of 144 ng/mL in vitro and 81.7 ng/mL ex vivo, respectively[1].