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TL12-186

Catalogue number:
T34888-5 mg
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
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CAS Number:

2250025-88-6

Purity:

≥98%

Molecular Formula:

C44H51ClN10O9S

Molecular Weight:

931.46

Alternative Names:

TL12 186 , TL12186

Product Description:

TL12-186 is a Cereblon-dependent kinase degrader that degrades CDK, BTK, FLT3, Aurora and other kinases.TL12-186 inhibits CDK2/cyclin A and CDK9/cyclin T1 with IC50s of 73 and 55 nM, respectively.