JGB1741
Catalogue number:
T22094-1 mg
Supplier:
Size:
1 mg
Product is available in:
CAS Number:
1256375-38-8
Purity:
≥95%
Molecular Formula:
C27H24N2O2S
Molecular Weight:
440.56
Alternative Names:
ILS-JGB-1741
- Data sheet: View or download
- MSDS: View or download
Product Description:
JGB1741 (ILS-JGB-1741) is a potent and selective inhibitor of SIRT1 with an IC50 of 15 µM. It modulates the Bax/Bcl2 ratio, cytochrome c release, and PARP cleavage, and increases acetylated p53 levels, leading to p53-mediated apoptosis. JGB1741 can be used in breast cancer studies.