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Linarin

Catalogue number:
T6S0653-1 mL
Size:
1 ml * 10 mM (in dmso)
£66.00
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CAS Number:

480-36-4

Purity:

≥95%

Molecular Formula:

C28H32O14

Molecular Weight:

592.55

Alternative Names:

Buddleoflavonoloside , Buddleoside , Acacetin-7-O-rutinoside , Acaciin , Linarine

Product Description:

1. Linarin (Acacetin-7-O-rutinoside) (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediated apoptotic pathways. 3. Linarin prevents A beta-induced neurotoxicity through the activation of PI3K/Akt, which subsequently inhibits GSK-3b and up-regulates Bcl-2. 4. The piperine significantly enhanced the oral absorption of Linarin in rats by inhibiting P-glycoprotein mediated cellular efflux during the intestinal absorption and likely simultaneously by inhibiting the metabolism of Linarin.