Samuraciclib hydrochloride
Catalogue number:
T10898-1 mg
Supplier:
Size:
1 mg
Product is available in:
CAS Number:
1805789-54-1
Purity:
≥98%
Molecular Formula:
C22H31ClN6O
Molecular Weight:
430.97
Alternative Names:
ICEC0942 hydrochloride , CT7001 hydrochloride
- Data sheet: View or download
- MSDS: View or download
Product Description:
Samuraciclib hydrochloride (ICEC0942 hydrochloride) is a potent, selective, ATP competitive and oral active CDK7 inhibitor with IC50 of 41 nM. The selectivity of Samuraciclib hydrochloride is 45-, 15-, 230- and 30-fold higher than CDK1, CDK2 (IC50 is 578 nM), CDK5 and CDK9 respectively. Samuraciclib hydrochloride inhibits the growth of breast cancer cell lines with GI50 values between 0.2-0.3 µM. Samuraciclib hydrochloride has anti-tumor effects.