6α-Prostaglandin I1
Catalogue number:
T36238-1 mg
Supplier:
Size:
1 mg
Product is available in:
CAS Number:
62777-90-6
Molecular Formula:
C20H34O5
Molecular Weight:
354.487
Alternative Names:
6α-Prostaglandin I1
- Data sheet: View or download
- MSDS: View or download
Product Description:
6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions. It promotes cyclic AMP accumulation in human thyroid slices and cells in a concentration-dependent manner but is about 10-fold less potent than the β-isomer and 100-fold less potent than PGI2 in eliciting this response. 6α-PGI1 exhibits an IC50 of 350 ng/ml for inhibition of ADP-induced platelet aggregation, nearly 900-fold higher than that of PGI2 (0.4 ng/ml).