9(10)-Nitrooleate
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1092676-99-7
≥95% (1:1 mixture of isomers)
A solution in ethanol
C18H33NO4 • C18H33NO4
654.9
9-nitro-9e-octadecenoic acid, 10-nitro-9e-octadecenoate, 9(10)-nitro-9-trans-octadecenoic acid, 9(10)-nitrooleic acid, oa-no2
A mixture of 9-nitrooleate and 10-nitrooleate; induces transactivation of PPARγ or Nrf2 in reporter assays using MCF-7 cells at ≥0.3 and ≥3 µM, respectively; induces transactivation of PPARγ, PPARδ, or PPARα in reporter assays using CV-1 cells; induces adipogenesis in 3T3-L1 preadipocytes and glucose uptake in differentiated 3T3-L1 adipocytes at 3 µM; decreases ischemia-induced increases in plasma levels of blood urea nitrogen, creatinine, and TNF-α and kidney levels of Mpo and IL-1β and reduces tubular necrosis and tubule dilation in a mouse model of renal ischemia-reperfusion injury at 500 µg/kg every six hours for 24 hours