K03861
Catalogue number:
CAY19921-5 mg
Supplier:
Size:
5 mg
Product is available in:
£88.00
Estimated delivery Tue 16 Dec
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
853299-07-7
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C24H26F3N7O2
Molecular Weight:
501.5
Alternative Names:
n-[4-[(2-
Product Description:
A Cdk2 inhibitor; binds to wild-type Cdk2, Cdk2C118L, Cdk2A144C, and Cdk2C118L/A144C (Kds = 50, 18.6, 15.4, and 9.7 nM, respectively); selectively inhibits proliferation of IL-3-stimulated Ba/F3 cells expressing FLT3-ITD over wild-type Ba/F3 cells (IC50s = ~0.001 and > 0.1 µM, respectively); inhibits human cytomegalovirus replication in primary human monocyte-derived macrophages (IC50 = 1.028 µM); inhibits spindle organization and chromosome alignment in meiosis I and prevents egg activation in isolated mouse oocytes at 10 µM