CS 2100
Catalogue number:
CAY14396-50 mg
Supplier:
Size:
50 mg
Product is available in:
£752.00
Estimated delivery Wed 17 Dec
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
913827-99-3
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C25H23N3O4S
Molecular Weight:
461.5
Alternative Names:
1-[[4-ethyl-5-
- MSDS: View or download
Product Description:
An S1P1 agonist; selectively induces GTPγS binding in CHO-K1 cells expressing human or rat S1P1 (EC50s = 4 and 1.5 nM, respectively) over those expressing human or rat S1P3 (EC50s = >20 and 7.4 µM, respectively); transiently reduces blood lymphocyte levels in rats with the levels returning to baseline within 24-48 hours at 0.1 and 1 mg/kg; reduces hind paw volume in a rat model of adjuvant-induced arthritis (ID50 = 0.44 mg/kg); decreases severity in a mouse model of EAE at 0.3 and 1 mg/kg