PQR620
Catalogue number:
CAY26656-10 mg
Supplier:
Size:
10 mg
Product is available in:
£390.00
Estimated delivery Mon 12 Jan
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1927857-56-4
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C21H25F2N7O2
Molecular Weight:
445.465986
Alternative Names:
5-[4,6-bis
Product Description:
An mTOR inhibitor (Ki = 10.8 nM); selective for mTOR over PI3K p110α (Ki = 4.2 µM) and a panel of 456 other kinases at 10 µM; has antiproliferative activity against a panel of 66 cancer cell lines (mean IC50 = 919 nM); induces cell cycle arrest at the G1 phase in A2058 and SKOV3 cancer cells at 5 µM; decreases the number of seizures per week in a Tsc1GFAP conditional knockout mouse model of epilepsy at 100 mg/kg per day