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WLB-89462

Catalogue number:
CAY39736-5 mg
Supplier:
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£97.00 Estimated delivery Tue 14 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

2849471-75-4

Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C21H29N5O3

Molecular Weight:

399.48686

Alternative Names:

2-[4-[2-ethyl-5-(3-methyl-5-isoxazolyl)-4-pyrimidinyl]-1-piperidinyl]-1-(4-morpholinyl)-ethanone

Product Description:

A σ2 receptor ligand; selectively binds to the σ2 receptor (Ki = 13 nM) over the σ1 receptor (Ki = 1,777 nM); prevents MPP+-induced decreases in the number of dopaminergic neurons in an in vitro model of neurodegeneration using primary rat neurons at 10 µM; improves short-term memory in the T-maze in rats at 10 mg/kg in a model of Alzheimer’s disease induced by hippocampal amyloid-β peptide injection