Angiopoietin-2 Protein, Rat, Recombinant (His)
Catalogue number:
TMPH-03240-1 mg
Supplier:
Size:
1 mg
Product is available in:
Molecular Weight:
60.1
Alternative Names:
Angiopoietin-2 , Angpt2 , Agpt2 , ANG-2
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Product Description:
Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. Angiopoietin-2 Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular_weight is 60.1 kDa and the accession number is O35462.