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Poziotinib hydrochloride

Catalogue number:
T8758-500 mg
Size:
500 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
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CAS Number:

1429757-68-5

Purity:

≥95%

Molecular Formula:

C23H22Cl3FN4O3

Molecular Weight:

527.8

Alternative Names:

NOV120101 hydrochloride , HM 781-36B hydrochloride

Product Description:

Poziotinib hydrochloride irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. It is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.