IQ-3
Catalogue number:
T8477-100 mg
Supplier:
Size:
100 mg
Product is available in:
CAS Number:
312538-03-7
Purity:
≥98%
Molecular Formula:
C20H11N3O3
Molecular Weight:
341.32
- Data sheet: View or download
- MSDS: View or download
Product Description:
IQ3 is a selective inhibitor of JNK3(JNK3, JNK1 and JNK2 with Kd of 66 nM, 240 nM and 290 nM, respectively). IQ 3 inhibits NF-κB/AP1 transcriptional activity in THP1-Blue cells with IC50 of 1.4 µM, also inhibits TNF-α and IL-6 production in vitro.