Antileishmanial agent-17
Catalogue number:
T78964-50 mg
Supplier:
Size:
50 mg
Product is available in:
CAS Number:
2934738-40-4
Molecular Formula:
C27H37N5O5
Molecular Weight:
511.61
- Data sheet: View or download
- MSDS: View or download
Product Description:
Antileishmanial agent-17, a coumarin hybrid, exhibits potent antileishmanial activity (IC50 <0.78 µM) while proving non-toxic to normal VERO cells. It specifically interacts with the folate pathway enzymes pteridine reductase and DHFR-TS. Efficacy against the promastigote form is highlighted by an IC50 value of 0.40 µM, and against the amastigote form, an IC50 of 0.68 µM, respectively.
