Naldemedine tosylate
Catalogue number:
T70929-100 mg
Supplier:
Size:
100 mg
Product is available in:
CAS Number:
1345728-04-2
Molecular Formula:
C39H42N4O9S
Molecular Weight:
742.84
Alternative Names:
S-297995 tosylate
- Data sheet: View or download
- MSDS: View or download
Product Description:
Naldemedine tosylate (S-297995) is an orally active µ-opioid receptor antagonist (PAMORA) with high binding affinities (K_i = 0.34, 0.43, 0.94 nM) and potent antagonist activities (IC_50 = 25.57, 7.09, 16.1 nM) towards human recombinant µ-, δ-, and κ-opioid receptors, respectively. It is utilized in research on opioid-induced constipation (OIC) and is anticipated to interact with the 3CL proenzyme encoded by the SARS-CoV-2 genome.
