Bupranolol HCl
Catalogue number:
T70506-50 mg
Supplier:
Size:
50 mg
Product is available in:
CAS Number:
15148-80-8
Molecular Formula:
C14H23Cl2NO2
Molecular Weight:
308.243
- Data sheet: View or download
- MSDS: View or download
Product Description:
Bupranolol is a non-selective beta blocker without intrinsic sympathomimetic activity (ISA), but with strong membrane stabilizing activity. Its potency is similar to propranolol. Bupranolol is quickly and completely absorbed from the gut. Over 90% undergo first-pass metabolism. Bupranolol has a plasma half life of about two to four hours, with levels never reaching 1 µg/l in therapeutic doses. The main metabolite is carboxybupranolol, 4-chloro-3-[3-(1,1-dimethylethylamino)-2-hydroxy-propyloxy]benzoic acid – that is, the methyl group at the benzene ring is oxidized to a carboxyl group –, of which 88% are eliminated renally within 24 hours.
