NRX-252114
Catalogue number:
T63516-50 mg
Supplier:
Size:
50 mg
Product is available in:
CAS Number:
2763260-39-3
Purity:
≥98%
Molecular Formula:
C22H12Cl2F3N3O2S
Molecular Weight:
510.32
Alternative Names:
NRX 252114 , NRX252114
- Data sheet: View or download
- MSDS: View or download
Product Description:
NRX-252114 (NRX252114) induces degradation of mutant β-catenin NRX-252114 is a potent enhancer of the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP, and is able to enhance the binding of pSer33/S37A β-catenin to β-TrCP with an EC50 of 6.5 nM and a Kd of 0.4 nM. Kd is 0.4 nM.
