MPT0G211 mesylate
Catalogue number:
T61753-100 mg
Supplier:
Size:
100 mg
Product is available in:
CAS Number:
2151854-33-8
Molecular Formula:
C18H19N3O5S
Molecular Weight:
389.43
- Data sheet: View or download
- MSDS: View or download
Product Description:
MPT0G211 mesylate is a powerful and selective HDAC6 inhibitor (IC50 = 0.291 nM), with high oral bioavailability. It exhibits remarkable selectivity for HDAC6 over other HDAC isoforms (>1000-fold selectivity). Additionally, MPT0G211 mesylate can effectively cross the blood-brain barrier. In preclinical studies using an Alzheimer's disease model, MPT0G211 mesylate has shown promising results in reducing tau phosphorylation and cognitive deficits. Furthermore, this compound exhibits anti-metastatic and neuroprotective effects, making it a potential candidate for anticancer interventions. [1] [2] [3].
