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Osunprotafib

Catalogue number:
T61699-1 mg
Size:
1 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
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CAS Number:

2489404-97-7

Purity:

≥95%

Molecular Formula:

C17H24FN3O4S

Molecular Weight:

385.45

Alternative Names:

AC 484 , Osunprotafib , AC484 , ABBV-CLS-484

Product Description:

Osunprotafib (ABBV-CLS-484) is a potent, orally bioavailable PTP1B/PTPN2 inhibitor in clinical trials for solid tumors. [1] Osunprotafib (ABBV-CLS-484) stimulates the tumor microenvironment and promotes natural killer cell and CD8 T cell function and enhances T cell anti-tumor immunity by enhancing JAK-STAT signaling and reducing T cell dysfunction. [2]