JH295 hydrate
Catalogue number:
T61061-25 mg
Supplier:
Size:
25 mg
Product is available in:
Molecular Formula:
C18H18N4O3
Molecular Weight:
338.36
- Data sheet: View or download
- MSDS: View or download
Product Description:
JH295 hydrate is a potent, irreversible, and selective NIMA-related kinase 2 (Nek2) inhibitor that inhibits cellular Nek2 by Cys22 alkylation (IC50 = 770 nM). JH295 hydrate is not active against the mitotic kinases Cdk1, Aurora B, or Plk1, and does not interfere with bipolar spindle assembly or the spindle assembly checkpoint [1].