AV123
Catalogue number:
T60316-100 mg
Supplier:
Size:
100 mg
Product is available in:
CAS Number:
233605-81-7
Molecular Formula:
C11H14N4O2
Molecular Weight:
234.25
- Data sheet: View or download
- MSDS: View or download
Product Description:
AV123 (compound 12) is a non-cytotoxic RIPK1 inhibitor with an IC50 of 12.12 µM. It blocks TNF-α-induced necroptosis with an EC50 of 1.7 µM, but not apoptotic cell death. AV123 can be used in the study of necrotic chronic conditions such as ischemia-reperfusion injury of the brain, heart, and kidney, inflammatory diseases, neurodegenerative diseases, and infectious diseases [1].
