A-674563 HCl (552325-73-2(free base))
Catalogue number:
T4444-1 mg
Supplier:
Size:
1 mg
Product is available in:
CAS Number:
2070009-66-2
Purity:
≥98%
Molecular Formula:
C22H23ClN4O
Molecular Weight:
394.9
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- MSDS: View or download
Product Description:
A-674563 is an orally available, ATP-competitive, and reversible inhibitor of Akt (Ki: 11 nM for Akt1) [1]. It exhibits inhibitory activity against PKA and Cdk2 (IC50: 16/46 nM) but is 10- to >1, 800-fold selective for Akt1 versus additional kinases in the CMGC, CAMK, and TK families [1].