MI-3454
Catalogue number:
T39584-1 mg
Supplier:
Size:
1 mg
Product is available in:
CAS Number:
2134169-43-8
Purity:
≥98%
Molecular Formula:
C32H35F3N8OS
Molecular Weight:
636.73
- Data sheet: View or download
- MSDS: View or download
Product Description:
MI-3454 is an orally active, selective and potent inhibitor of Menin-MLL1 interaction that inhibits the proliferation and induces differentiation of acute leukemia cells with MLL1 translocation or NPM1 mutation.MI-3454 induces complete remission or regression of leukemia in a mouse model of leukemia with MLL1 rearrangement or NPM1 mutation through the down-regulation of key genes involved in leukemogenesis. complete remission or remission.