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Olorofim

Catalogue number:
T27300-100 mg
Size:
100 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
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CAS Number:

1928707-56-5

Purity:

≥98%

Molecular Formula:

C28H27FN6O2

Molecular Weight:

498.55

Alternative Names:

Olorofim , F901318 , F-901318

Product Description:

Olorofim(F-901318)is a novel selective antifungal compound targeting pyrimidine biosynthesis in mycobacteria, with inhibitory effect on Aspergillus fumigatus DHODH (IC50: 44 nM), but little inhibitory effect on human DHODH (>100 uM).Olorofim has good efficacy against a variety of pathogenic filamentous and dimorphic fungi, such as Penicillium spp, P. dermatitidis spp and Fusarium spp.

Olorofim
Olorofim