Bromfenac sodium hydrate
Catalogue number:
T2403-10 mg
Supplier:
Size:
10 mg
This product is no longer available to order.
CAS Number:
120638-55-3
Purity:
≥90%
Molecular Formula:
C15H12BrNO3·3/2H2O·Na
Molecular Weight:
383.17
Alternative Names:
Bromfenac monosodium salt sesquihydrate , Bromfenac sodium sesquihydrate
- Data sheet: View or download
- MSDS: View or download
Product Description:
Bromfenac sodium hydrate (Bromfenac monosodium salt sesquihydrate) is the sodium salt form of bromfenac, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory properties. Upon ophthalmic administration, bromfenac binds to and inhibits cyclooxygenase II (COX II), an enzyme that converts arachidonic acid to cyclic endoperoxides, which are prostaglandin (PG) precursors. By inhibiting PG formation, bromfenac prevents PG-induced inflammation, vasodilation, leukocytosis, disruption of the blood-aqueous humor barrier, increased vascular permeability, and elevated intraocular pressure (IOP).