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GNE-617 hydrochloride (1362154-70-8 free base)

Catalogue number:
T22801-5 mg
Size:
5 mg
Product is available in:
  • UK
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Molecular Formula:

C21H16ClF2N3O3S

Molecular Weight:

463.88

Alternative Names:

GNE-617 hydrochloride

Product Description:

GNE-617 hydrochloride is a potent and competitive inhibitor of nicotinamide phosphoribosyltransferase (IC50: 5nM). GNE-617 hydrochloride reduces the NAD levels in a > 95% reduction in both NAPRT1-deficient and NAPRT1-proficient cell lines and exerts (EC50: 0.54nM to 4.69nM).