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CAS Number:
2137030-98-7
Purity:
98.73%
Molecular Formula:
C26H29Cl4FN6O3
Molecular Weight:
634.36
Alternative Names:
Ensartinib dihydrochloride , X-396 dihydrochloride
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Ensartinib hydrochloride (X-396 dihydrochloride) is a potent new-generation ALK inhibitor with high activity against CNS metastases and a broad range of known crizotinib-resistant ALK mutations. It potently inhibits both wild-type ALK and ALK variants (C1156Y, F1174, G1202R, L1196M, S1206R, and T1151 mutants) with in vitro IC50s of <4 nM.