DM4-SMe
Catalogue number:
T11059-25 mg
Supplier:
Size:
25 mg
Product is available in:
CAS Number:
796073-68-2
Molecular Formula:
C39H56ClN3O10S2
Molecular Weight:
826.46
- Data sheet: View or download
- MSDS: View or download
Product Description:
DM4-SMe is a cytotoxic part of antibody-drug conjugates (ADCs) and a metabolite of antibody-maytansin conjugates (AMCs) and tubulin inhibitors, which can also be stabilized by disulfide bonds or thioether The bond binds to the antibody. The IC50 of DM4-SMe on KB cells was 0.026 nM.
