Tuvusertib
Catalogue number:
T10406-10 mg
Supplier:
Size:
10 mg
Product is available in:
CAS Number:
1613200-51-3
Purity:
≥98%
Molecular Formula:
C16H12F2N8O
Molecular Weight:
370.32
Alternative Names:
M1774 , ATR inhibitor 1
- Data sheet: View or download
- MSDS: View or download
Product Description:
Tuvusertib (M1774) is an orally available ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor (Ki< 1 µΜ) with selective and potentially antitumor activity.Tuvusertib selectively inhibits ATR activity and blocks downstream phosphorylation of serine/threonine protein kinase checkpoint kinase 1 (CHK1), thereby inhibits DNA damage checkpoint activation, disrupting DNA damage repair and inducing apoptosis in tumor cells.
