TL12-186
Catalogue number:
CAY40970-50 mg
Supplier:
Size:
50 mg
Product is available in:
£1168.00
Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2250025-88-6
Purity:
≥95%
Formulation:
A solid
Molecular Formula:
C44H51ClN10O9S
Molecular Weight:
931.5
Alternative Names:
n-[2-[2-[2-
Product Description:
A PROTAC that drives the degradation of multiple kinases; binds to CRBN (IC50 = 12 nM) and inhibits 193 kinases by >90% in cell-free assays; inhibits the proliferation of wild-type CRBN-expressing but not CRBN-/- MOLM-14 and MOLT-4 cells from 1-10,000 nM