KRAS G12D-Specific TCR Lentivirus (Clone 10)

KRAS G12D-Specific TCR Lentivirus (Clone 10) are replication incompetent, HIV-based, VSV-G-pseudotyped lentiviral particles ready to transduce nearly all types of mammalian cells, including primary and non-dividing cells. These viruses transduce cells with a TCR (T cell receptor) (clone 10) that specifically recognizes the human antigen KRAS (Kirsten rat sarcoma virus) G12D, and in which the TCR α chain and β chain are linked by P2A. The lentiviruses also transduce a puromycin selection marker. Mouse TCR constant regions were used in this construct to boost expression.

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