AJ2-30
Catalogue number:
CAY40667-5 mg
Supplier:
Size:
5 mg
Product is available in:
£595.00
Estimated delivery Wed 24 Dec
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2700322-79-6
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C23H22N4
Molecular Weight:
354.5
Alternative Names:
9-ethyl-n-(1-
Product Description:
An inhibitor of SLC15A4; selective for SLC15A4 over SLC15A3 at 5 µM; reduces CPG-2216-induced increases in IFN-α in primary human plasmacytoid dendritic cells; inhibits MDP-mediated NOD2 signaling in a reporter assay using A549 cells expressing membrane-localized SLC15A4 (IC50 = 2.6 µM); reduces CPG-2006- or R-837-induced increases in IFN-α and IL-6 in SLE patient-derived PBMCs; reduces CPG-2216-DOTAP complex-induced IFN-α, IFN-β, and IFN-γ production in mice at 50 mg/kg