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GSK329

Catalogue number:
CAY40666-10 mg
Supplier:
Size:
10 mg
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
£428.00 Estimated delivery Wed 24 Dec
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1268490-12-5

Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C19H14Cl2F3N5O2

Molecular Weight:

472.3

Alternative Names:

n-[3,5-dichloro-4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]-n′-[3-(trifluoromethyl)phenyl]-urea

Product Description:

A TNNI3K inhibitor and sorafenib derivative (IC50 = 10 nM); selective for TNNI3K over VEGFR2, p38α, and B-RAF (IC50s = 400, 800, and >2,000 nM, respectively); reduces superoxide levels in isolated left ventricular tissues and infarct size in a mouse model of myocardial ischemia-reperfusion injury induced by LAD coronary artery occlusion at 2.75 mg/kg