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MCU i4

Catalogue number:
CAY39993-5 mg
Supplier:
Size:
5 mg
Product is available in:
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£32.00 Estimated delivery Wed 24 Dec
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

371924-24-2

Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C23H27N3O2

Molecular Weight:

377.5

Alternative Names:

4-[[4-(diethylamino)phenyl]amino]-6-methyl-3-quinolinecarboxylic acid, ethyl ester, mitochondrial calcium uptake inhibitor 4

Product Description:

A negative modulator of mitochondrial calcium uptake; selectively decreases mitochondrial over cytosolic histamine-induced calcium uptake, but also decreases the mitochondrial membrane potential, in HeLa cells at 10 µM; binds to Micu1 in a cell-free assay (Kd = 8.4 µM for the mouse protein); decreases myotube width in differentiated C2C12 skeletal muscle myoblasts in an in vitro model of myotube growth; protects against ferroptosis induced by RSL3, erastin, or glutamate in HT22 hippocampal cells at 2.5 µM