BAY-2416964
Catalogue number:
CAY36939-5 mg
Supplier:
Size:
5 mg
Product is available in:
£83.00
Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2242464-44-2
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C18H18ClN5O3
Molecular Weight:
387.8
Alternative Names:
6-(4-chloro
Product Description:
An AhR antagonist (IC50 = 22 nM in U87 cells); decreases kynurenic acid-induced mRNA expression of CYP1A1 and AHRR in LPS-stimulated isolated human monocytes at 100 nM; increases CD3-, CD28-, and IL-2-induced IFN-γ production in isolated human naïve CD4+ T cells from 30-1,000 nM; reduces tumor volume, increases CD8+ T cell and NK cell tumor infiltration, and decreases GR1+ myeloid cell and CD206+ M2 macrophage tumor infiltration in a B16/F10-OVA murine melanoma model at 30 mg/kg, p.o.