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4E2RCat

Catalogue number:
CAY35894-50 mg
Supplier:
Size:
50 mg
Product is available in:
  • UK
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£207.00 Estimated delivery Wed 24 Dec
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

432499-63-3

Purity:

≥98% (mixture of isomers)

Formulation:

A solid

Molecular Formula:

C22H14ClNO4S2

Molecular Weight:

455.9

Alternative Names:

2-chloro-5-[5-[[4-oxo-3-(phenylmethyl)-2-thioxo-5-thiazolidinylidene]methyl]-2-furanyl]-benzoic acid

Product Description:

An inhibitor of the eIF4E-eIF4G protein-protein interaction (IC50 = 13.5 µM); reduces mRNA translation without inducing apoptosis in L-132 cells at 12.5 µM; decreases intracellular and extracellular SARS-COV titers and the percentage of cells expressing spike glycoprotein in SARS-COV-infected L-132 cells at 6 µM