ML-241 (hydrochloride)
Catalogue number:
CAY40400-10 mg
Supplier:
Size:
10 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2070015-13-1
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C23H24N4O • HCl
Molecular Weight:
408.9
Alternative Names:
2-(2,3-di
Product Description:
A selective inhibitor of p97 (IC50 = 0.11 µM); selective for the p97 D2 domain; disrupts the ERAD pathway, preventing the degradation of p97-dependent proteasome substrates in a reporter assay using HeLa cells (IC50 = 3.5 µM) and inducing the accumulation of ubiquitin conjugates in the nuclear plus membrane and cytosolic compartments of SW403 cells at 5 and 10 µM