5,7,3',4'-Tetramethoxyflavone
Catalogue number:
CAY40272-100 mg
Supplier:
Size:
100 mg
Product is available in:
£166.00
Estimated delivery Thu 2 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
855-97-0
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C19H18O6
Molecular Weight:
342.3
Alternative Names:
2-(3,4-
Product Description:
A flavone with diverse biological activities; selectively inhibits MRP1 over MRP2 (IC50s = 7.9 and >50 µM, respectively); inhibits LPS-induced nitric oxide (NO) release in primary mouse peritoneal macrophages from 0.03-30 µM; active against P. falciparum (IC50 = 4.06 µg/ml); is cytotoxic to B16/F10 melanoma cells at 20 µM; inhibits IL-33-induced production of CCL2 and CCL5 in primary human mast cells at 50 and 100 µM; decreases the synovial fluid levels of PGE2, IL-1β, and TNF-α in a rat model of surgically induced osteoarthritis at 100 mg/kg