www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

Dienestrol

Catalogue number:
CAY38954-100 mg
Supplier:
Size:
100 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£88.00 Estimated delivery Tue 16 Dec
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

84-17-3

Purity:

≥95%

Formulation:

A solid

Molecular Formula:

C18H18O2

Molecular Weight:

266.33432

Alternative Names:

4,4′-(1,2-diethylidene-1,2-ethanediyl)bis-phenol, dienoestrol, nsc 59809

Product Description:

A synthetic non-steroidal estrogen receptor agonist and an active metabolite of diethylstilbestrol; binds to ERα and ERβ (Kis = 0.05 and 0.03 nM, respectively); activates ERα in a reporter assay (EC50 = 3.23 nM); inhibits porcine microtubule assembly and induces disassembly of preformed microtubules at 50 and 100 µM, respectively, in cell-free assays; oral administration to pregnant rats during gestation and lactation decreases sperm motility and viability and induces prostatitis in mature male offspring from 1.5-6.25 µg/kg; induces abortions when administered to pregnant rats at 50 and 75 µg/kg